Granulation Suite (HSM, FBD, Blender, Coater, Sifter & Milling)
The granulation suite for pharmaceutical manufacturing is a fully integrated processing solution designed for the production of solid dosage forms. It combines key equipment including High Shear Mixer (HSM), Fluid Bed Dryer (FBD), Blender, Coater, Sifter, and Milling systems within a controlled, GMP-compliant environment.
This system enables seamless material transfer across all process stages, ensuring consistent product quality, reduced contamination risk, and efficient operations. By integrating mixing, granulation, drying, blending, coating, and sizing, it supports reliable and scalable pharmaceutical production.
Key Features
- Integrated granulation and processing workflow
- Includes HSM, FBD, Blender, Coater, Sifter, and Milling systems
- Ensures consistent product quality and uniformity
- Reduces contamination through controlled material handling
- Designed for scalable pharmaceutical manufacturing
Related products
Frequently Asked Questions
A pharmaceutical granulation suite is an integrated set of equipment for converting API and excipient powders into granules for tablet and capsule manufacturing. It typically includes a High Shear Mixer (HSM) for wet granulation, Fluid Bed Dryer (FBD) for drying, blender for mixing, coater for film coating, sifter for screening, and milling equipment for particle sizing.
A high shear mixer (HSM) wet granulates pharmaceutical powder blends by combining API, excipients, and binder liquid under intense mechanical agitation. The impeller and chopper create uniform, dense granules with defined particle size, improving flowability, compressibility, and content uniformity for downstream tablet compression and capsule filling operations.
A fluid bed dryer (FBD) suspends wet granules in a controlled stream of heated, filtered air, enabling rapid and uniform moisture removal through evaporation. Temperature, airflow velocity, and inlet air humidity are precisely controlled to achieve the target residual moisture level without damaging thermolabile APIs or causing granule attrition or over-drying.
Wet granulation uses a liquid binder in a high shear mixer to agglomerate powders into granules, followed by drying in an FBD—producing dense, flowable granules ideal for most APIs. Dry granulation (roller compaction or slugging) binds powders without liquid, used for moisture-sensitive or heat-sensitive APIs that cannot tolerate the wet granulation process.
A pharmaceutical coater applies thin film coatings to tablets or granules using a rotating pan or fluid bed system. Film coatings modify drug release (immediate, extended, or enteric), improve tablet aesthetics, mask bitter taste, protect moisture-sensitive APIs, and facilitate swallowability—meeting pharmacopoeial and patient-centric drug product design requirements.
Sifters (vibratory screens) classify granules by particle size, removing oversized agglomerates and fines to ensure consistent granule size distribution before blending and compression. Mills (hammer, conical, or oscillating) reduce oversized granules to target particle size ranges, improving blend homogeneity, tablet weight uniformity, and content uniformity in the final solid dosage form.
Yes. GMP granulation suites feature 316L stainless steel product contact surfaces, contained material transfer between units, integrated dust extraction, explosion-proof (ATEX) options for solvent-based processes, and full IQ/OQ/PQ qualification support. They comply with FDA 21 CFR Part 211, EU GMP, and ICH Q8/Q10 requirements for solid dosage form manufacturing.
Pharmaceutical blenders—bin blenders, V-blenders, or double cone blenders—mix granules with lubricants (magnesium stearate) and other blend components to achieve content uniformity prior to tablet compression. Validated blending times, fill levels, and rotation speeds ensure the API is homogeneously distributed throughout the blend, meeting pharmacopoeial content uniformity specifications.
Yes, all our products are designed and sourced to meet international regulatory standards, including GMP, USFDA, EU-GMP, WHO, and other relevant compliance requirements.
Absolutely. Our solutions are engineered for seamless integration with existing systems, ensuring minimal disruption and optimal performance within your current setup.
Yes, our team offers technical consultation to help you choose the most suitable product based on your process requirements, facility design, and compliance needs.
Yes, all our products are aligned with our turnkey execution approach, ensuring compatibility with overall facility design, engineering, and operational requirements.
Yes, we provide customised solutions tailored to your process, capacity, and regulatory requirements to ensure optimal performance and efficiency.
Our products are used across pharmaceutical manufacturing, biotechnology, nutraceuticals, research laboratories, and regulated healthcare environments.
We follow strict quality standards and work with trusted technologies and manufacturing processes to ensure consistent performance, durability, and compliance.
Yes, we offer ongoing technical support to ensure smooth operation, performance optimisation, and long-term reliability of all supplied systems and components.
